PhD Molecular Biologist in Clinical Genomics

REGION ÖREBRO LÄN · Vollzeit

Box 1613, Örebro, Schweden

Are you a PhD molecular biologist with experience in laboratory NGS work and method development? Do you want to develop and evaluate new genomic methods for research and clinical diagnostics in cancer? Then this might be the role for you. Clinical Genomics is a unit within the Clinical Research Center, Region Örebro län, working closely with the Clinical Laboratory Medicine Operations and Örebro University. We are part of Clinical Genomics, SciLifeLab, and Genomic Medicine Sweden (GMS). We develop and support the implementation of genomic methods for clinical diagnostics and offer research services in advanced sequencing. The operations are currently in an expansive phase through Region Örebro län's investments in precision medicine and the Comprehensive Cancer Centre (CCC). With us, you will have the opportunity to work in a research-oriented environment where new knowledge is quickly converted into clinical benefit. You are offered an independent role with great opportunities to influence the development of the operations and, together with an experienced team, develop the future of diagnostics in cancer genomics. Responsibilities We are seeking a PhD molecular biologist who wants a key role in the laboratory development of methods in cancer genomics. The position is laboratory-based and operations-focused, suited for someone who wants to use their scientific expertise to develop robust and quality-assured methods for research services and clinical diagnostics. A particular development area is liquid biopsy and analysis of circulating tumor DNA (ctDNA), where we are working to develop new methods for clinical use. You will independently plan and conduct genomic projects within our research services and lead method development projects with the aim of creating robust, standardized, and quality-assured workflows. The work includes the entire chain from project planning and experimental design to practical laboratory work, optimization, validation, documentation, reporting, and handover to diagnostics. You are expected to contribute scientific expertise in method development and implementation of new NGS-based analyses and be an active driver in the development of new research projects and genomic methods. The work takes place in close collaboration with researchers, clinicians, bioinformaticians, and other colleagues within Clinical Genomics, but you are responsible for planning, prioritizing, and advancing your projects. Qualifications We are looking for someone who has: a PhD in molecular biology, biomedicine, or another relevant field documented experience with laboratory NGS work experience in method development in cancer genomics good ability to communicate in Swedish and English, both verbally and in writing It is meritorious if you have experience with: work in a quality-assured laboratory operation, according to ISO 15189 or equivalent experience validating and implementing molecular genetic or NGS-based methods in clinical operations automated laboratory workflows experience with liquid biopsy, ctDNA, or other analyses of low-frequency genetic variants collaboration with bioinformaticians and clinical specialists project management or coordination of cross-professional development projects It is important that you enjoy practical and operations-focused method development work. The role involves converting scientific methods into robust, reproducible, and documented workflows that can be used in research services and clinical diagnostics. We are looking for someone who is initiative-taking, structured, and solution-oriented. You have the ability to independently plan, conduct, document, and complete method development projects as well as prioritize and make well-founded decisions. At the same time, you enjoy collaborating and communicating with different professions. We place great emphasis on personal suitability. Application Your application should include a CV and cover letter. Certificates, grades, diplomas, and similar documents should be submitted at a potential interview. If you are or have previously been employed by Region Örebro län, we will take internal references from your current or previous manager, if you become relevant for employment. Background checks from the Police Authority may be conducted in accordance with applicable legislation. As an employee of Region Örebro län, you are covered by secure collective agreements. Read more about terms and benefits. We set salaries individually and differentially. Read more about salary and salary statistics. We place our permanent employees and in some cases also fixed-term employees in crisis placement positions. Read more about what this entails. About the Operations Region Örebro län is one of the county's largest employers. Together with 11,000 colleagues, you can create a better life for those we exist to serve. With us there are meaningful and socially important jobs where you can make a difference in residents' daily lives, health, and quality of life. Around the clock, year-round, we are responsible for health care, dental care, and the county's public transport. We also have regional development responsibility in the county and a mandate to contribute to cultural life. Other Information Welcome with your application! 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