Research Assistant in Translational Pharmacokinetics-Pharmacodynamics

Description:

The Department of Pharmacy at Uppsala University has an interdisciplinary environment that is central to the pharmaceutical field. With research at the forefront, world-class education, and extensive collaboration with the surrounding society, we constitute an important engine in the development of the pharmaceutical field. In this inspiring environment, internationally high-quality research takes place with great significance. Among our core competencies are pharmacokinetics-pharmacodynamics, in vitro ADME models, advanced in vivo methods, modeling and simulation, biological drugs, as well as patient-related and societal aspects ranging from individual drug use to pharmaceutical policy. Our scientific focus areas (selected) Pharmacokinetics & Pharmacodynamics • Pharmacometrics • Clinical Pharmacy • Advanced Drug Formulation • Molecular Galenic Pharmacy • Biological Drugs • Pharmacoepidemiology • Social Pharmacy More information www.farmaci.uu.se Project: Biomarkers for Chemotherapy-Induced Peripheral Neuropathy Duties: The project encompasses research on biomarkers for chemotherapy-induced peripheral neuropathy (CIPN), with particular focus on neurofilament light chain (NfL) in serum and the role of barriers in the central and peripheral nervous system in the development of CIPN. The data generated experimentally will be used for pharmacokinetic-pharmacodynamic modeling as a translational tool to characterize the relationship between exposure to cytostatic drugs in plasma and in CIPN-relevant tissues as well as biomarkers in serum. The study encompasses several microtubule-inhibiting drugs as well as antibody-drug conjugates (ADCs). Qualifications: The applicant should have a degree in pharmacy, medicine, engineering/natural sciences or a related field. Applicants should have documented experience with animal studies in chemotherapy-induced peripheral neuropathy (CIPN), drug bioanalysis with UPLC-MS/MS, bioanalysis of NfL, and pharmacokinetic-pharmacodynamic modeling and simulation. We place great emphasis on personal suitability, motivation, and interest in research aimed at improving safety in treatment with cytostatic drugs. The applicant should be able to express themselves well, both orally and in writing, in English. Applicants should be able to work independently and in groups. Meritorious: Good understanding of the structure and function of barriers in the central and peripheral nervous system. Basic knowledge of pharmacokinetics of antibody-drug conjugates. Practical experience with analysis and modeling of pharmacokinetic-pharmacodynamic data. Interest in and good ability to write scientific texts in English is meritorious. About the Employment The employment is fixed-term, 4 months. Full-time (100%). Start date September 1, 2026 or by agreement. Location: Uppsala Information about the employment is provided by: University Lecturer Irena Loryan, [email protected] Welcome to submit your application no later than July 12, 2026, UFV-PA 2026/2374. Uppsala University is a broad research university with strong international standing. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all 7,500 employees and 53,000 students who with curiosity and commitment make Uppsala University one of the country's most exciting workplaces. Read more about our benefits and what it is like to work at Uppsala University https://uu.se/om-uu/jobba-hos-oss/ The employment may be subject to security vetting. In security vetting, a requirement for employment is that the applicant is approved. We decline offers of recruitment and advertising assistance. Applications are received in Uppsala University's recruitment system. Labor union representatives: Saco-S - [email protected], Seko - [email protected], ST (OFR/S) - [email protected] Open to All We focus on your competence, not your other circumstances. We are open to adapting the role or workplace according to your needs.The Department of Pharmacy at Uppsala University has an interdisciplinary environment that is central to the pharmaceutical field. With research at the forefront, world-class education, and extensive collaboration with the surrounding society, we constitute an important engine in the development of the pharmaceutical field. In this inspiring environment, internationally high-quality research takes place with great significance. Among our core competencies are pharmacokinetics-pharmacodynamics, in vitro ADME models, advanced in vivo methods, modeling and simulation, biological drugs, as well…

Overview

Type

job

Status

active

Visibility

public

City

Uppsala

Address

box 256

GPS

59.8710738, 17.5946002copyopen in

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6

Published

29. 7. 2026

Edited

5. 8. 2026

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