Research Assistant in Developmental Biology

Stockholms Universitet · plný úvazek

Institutionen för molekylär biovetenskap Wenner-Gr, Stockholm, Švédsko

The Department of Molecular Bioscience, Wenner-Gren Institute (MBW) conducts experimental basic research in molecular cell biology, integrative biology, and infection and immunobiology. The research environment is characterized by modern and advanced methodology and has a strong international profile. MBW is one of the larger departments within the Faculty of Natural Sciences at Stockholm University with approximately 30 research groups and about 180 employees, of which approximately 50 are doctoral students. The position is affiliated with Professor Samakovlis's research group at the Department of Molecular Biosciences, Wenner-Gren Institute. More information about us can be found at: Department of Molecular Bioscience Wenner-Gren Institute. Duties Lung Development and Regeneration The project combines genetic cell marking and FACS-based cell sorting with snRNA-seq and snATAC-seq (Multiome) from the same cell nuclei, together with spatially resolved methods to: 1) analyze differences in gene expression and chromatin accessibility between cell types and cell states along the airway epithelium. 2) define enhancer-driven gene regulatory networks (GRN = regulatory elements, transcription factors & target genes) that determine and maintain airway epithelial cell identity 3) test GRNs (e.g., synthetic enhancers) and regulators (e.g., transcription factors) and their effects on cell identity and cellular functions in vitro. Analysis of multiomics data, in vitro tissue culture, in situ analysis of gene expression Qualifications Special emphasis will be placed on experimental skill and Master's courses in bioinformatics and statistics. About the Employment The employment is full-time and limited to a maximum of 6 months. Start date by agreement. What We Offer With us you get the dynamic interplay between higher education and research that makes Stockholm University an exciting and creative environment. You work in an international environment and receive favorable conditions. The university is located in the National City Park with good connections to the city center. Stockholm University is committed to being a workplace free from discrimination and providing equal rights and opportunities for all. Contact Information about the position is provided by Professor Christos Samakovlis, [email protected]. Application You apply for the position via Stockholm University's recruitment system. Attach a cover letter and CV as well as any attachments requested in the application form. As an applicant, you are responsible for ensuring that your application is complete and submitted to the university no later than the final application deadline. Instructions for applicants can be found on the website: applying for a position. Stockholm University contributes to the development of a sustainable democratic society through knowledge, enlightenment, and the pursuit of truth.