PhD Student in Medical Science

Would you like to work with clinical research, supported by competent and pleasant colleagues in an international environment? Would you like an employer that invests in sustainable employee partnerships and offers secure, favorable working conditions? Welcome to apply for a position as a PhD student in Medical Science at Uppsala University. The Department of Medical Sciences is a large clinical department with approximately 250 employees and over 900 individuals affiliated through Akademiska Hospital. The department has a broad research profile with strong research groups in various areas. Research is conducted in close connection with clinical operations at Akademiska Hospital and includes both basic studies on disease causes as well as development and evaluation of improved diagnostics and new treatment methods. More about the department's activities can be found at https://www.uu.se/institution/medicinska-vetenskaper/ The position is placed in the Clinical Chemistry research group, which consists of several independent researchers with projects in laboratory diagnostics and related areas. Within the group, extracellular vesicles as biomarkers constitute a separate research line, with studies in hemostasis, vascular disease, and inflammation. The current project is conducted in collaboration with clinical and preclinical researchers at the Karolinska Institute, Danderyd Hospital, and Livio Fertility Center. Duties Assisted reproduction (IVF) is associated with an increased risk of blood clots during early pregnancy, but the mechanisms behind this remain unclear and there are no laboratory methods to assess risk in individual patients. Extracellular vesicles (EV) are nano-sized particles released from body cells, carry procoagulant properties, and participate in reproductive signaling. They may therefore be the missing link between reproduction and hemostasis in current understanding. The project examines how EVs change during IVF treatment, their relationship to hemostatic activation and clinical outcomes, and whether they can be used as biomarkers. Analyses are performed using existing longitudinal biobank material and in a prospective cohort. The PhD student will be part of the national research school BioLabX (Biomedical Analysts for Excellence), which educates future teachers and researchers in healthcare and medical science. The work is primarily laboratory-based and builds on immunological methods and high-sensitivity flow cytometry for characterization of extracellular vesicles at the individual vesicle level. The work includes handling of clinical samples from biobank and prospective collection, setup and validation of antibody panels, analytical quality assurance, and integration of EV data with hemostasis measurements and clinical outcome data. The position includes higher education pedagogy training as well as teaching and mentoring of students in biomedical laboratory science programs at Uppsala University, corresponding to a maximum of 20 percent of full-time. Qualification Requirements To be eligible for admission to doctoral level studies, an applicant must have completed an advanced level degree, fulfilled course requirements of at least 240 higher education credits, of which at least 60 credits at advanced level, or otherwise acquired substantially equivalent knowledge within or outside the country. Applicants are expected to have a 3-year undergraduate degree from biomedical analyst education and a master's degree corresponding to 60 higher education credits at advanced level in a relevant field (biomedical laboratory science, medicine, biomedicine, pharmacy, medical science, or equivalent). We are looking for a motivated candidate with interest in biomedical laboratory science, extracellular vesicles, and hemostasis. Great emphasis will be placed on personal skills such as communication and collaboration abilities. Applicants must have good knowledge of Swedish and English in speech and writing. You are expected to be able to work independently but also collaborate with other group members. The applicant is expected to actively participate in teaching and mentoring of students corresponding to a maximum of 20% of full-time. Applicants should have experience with basic methods in biomedical laboratory science and immunology, as well as sample handling and preanalytical handling of clinical samples. Desirable/Meriting Experience Experience with flow cytometry is meriting, as is work with extracellular vesicles, hemostasis, and coagulation. Experience with clinical studies is meriting, as is documented participation in teaching. Great weight is placed on personal suitability. The application should contain a brief description of research interests and relevant experience, CV, copies of diplomas and identification, and any translations thereof. If available, also submit letters of recommendation or contact information for previous research supervisors. Provisions for PhD students are found in the Higher Education Ordinance Chapter 5 §§ 1-7 and in the university's rules and guidelines. About the Position The position is time-limited, according to HF Chapter 5 § 7. Full-time. Start date by agreement. Location: Uppsala. Information about the position is provided by: Fariborz Mobarrez, [email protected] Welcome to submit your application by September 24, 2026, UFV-PA 2026/2505. Uppsala University is a broad research university with strong international standing. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all 7,500 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of the country's most exciting workplaces. Read more about our benefits and what it's like to work at Uppsala University https://uu.se/om-uu/jobba-hos-oss/ The position may be subject to security clearance. Security clearance is a requirement for employment, and the applicant must be approved. We decline offers of recruitment and advertising assistance. Applications are received through Uppsala University's recruitment system. Trade union representatives: Saco-S - [email protected], Seko - [email protected], ST (OFR/S) - [email protected]

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